Based on 163 reference(s) in Google Scholar 8 10 163

Axon 2751

CAS [223104-29-8]

MF C21H19F2NO3
MW 371.38

  • Purity: 99%
  • Soluble in DMSO



SEA0400 is a potent and selective inhibitor of the Na+-Ca2+ exchanger (NCX). IC50 values of SEA0400 were 33, 5.0, 8.3, 90 and 92 nM in cultured neurons, astrocytes, microglia, dog sarcolemmal vesicles and cultured rat myocytes, respectively. SEA0400 protects astrocytes against Ca2+ paradox-like injury and reduces cerebral ischemic damage in rats with a transient middle cerebral artery occlusion.

KEYWORDS: SEA0400 | supplier | NCX inhibitor | SEA 0400 | SEA-0400 | CAS [223104-29-8] | Non Selective (Ions; Na+Ca2+) | NCX | Inhibitor | Proteins

Size Unit Price Stock
10 mg €135.00 In Stock
50 mg €485.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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