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Axon 2708
CAS [852918-02-6]
MF C21H17ClFN3O4SMW 461.89
NMDA receptor antagonist selective for NR2A- over NR2B-containing receptors (pIC50 values of 6.8 and 4.3, respectively). The degree of inhibition produced by TCN 201 is dependent on the concentration of the GluN1-site co-agonist, glycine (or D-serine), and is independent of the glutamate concentration. TCN-201 is a negative allosteric modulator of glycine binding.
KEYWORDS: TCN-201 | supplier | NR2A antagonist | TCN201 | TCN 201 | CAS [852918-02-6] | Axon Medchem | Axon 2708 | Glutamate | NMDA | Antagonist | Ion Channels
N-(4-(2-Benzoylhydrazinecarbonyl)benzyl)-3-chloro-4-fluorobenzenesulfonamide
[852918-02-6]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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