EED226

Based on 4 reference(s) in Google Scholar 8 10 4

Axon 2701

CAS [2083627-02-3]

MF C17H15N5O3S
MW 369.40

  • Purity: 99%
  • Soluble in DMSO

EED226

Description

EED226 is a first-in-class, potent, selective and orally bioavailable PRC2 inhibitor (IC50 values of 23.4 nM and 53.5 nM with H3K27me0 peptide and the mononucleosome as the substrates, respectively) that directly binds to the H3K27me3 binding pocket of EED. EED226 effectively induced tumor regression in a mouse xenograft model.

KEYWORDS: EED226 | supplier | PRC2 inhibitor | EED-226 | EED 226 | CAS [2083627-02-3] | PRC | Inhibitor | Proteins | EED | PRC | EZH1 | EZH2

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Size Unit Price Stock
5 mg €105.00 In Stock
25 mg €355.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €160.00 In Stock
2 x 25 mg €520.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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