WAY-200070 - WAY-00005

Based on 56 publications in PubMed 8 10 56

Axon 2697

CAS [440122-66-7]

MF C13H8BrNO3
MW 306.11

  • Purity: 99%
  • Soluble in 0.1N NaOH(aq) and DMSO
Recently added

WAY-200070

Description

Brain penetrant ERβ-selective agonist (IC50 values 155 nM and 2 nM for ERα and ERβ, respectively) that increases key synaptic proteins in vivo, including PSD-95, synaptophysin and the AMPA-receptor subunit GluR1 and increases dendritic branching and spine number. WAY 20070 regulates hippocampal synaptic plasticity and improve hippocampus-dependent cognition, and shows antidepressant and anxiolytic-like effects in vivo. Potential novel therapeutic agent for the prevention and treatment of photoaging.

KEYWORDS: WAY-200070 | supplier | ERβ agonist | WAY-00005 | WAY200070 | WAY 200070 | WAY00005 | WAY 00005 | CAS [440122-66-7] | Axon Medchem | Axon 2697 | Estrogen | Nuclear Receptor | Brain penetrant | PSD-95 | synaptophysin | AMPA | GluR1 | dendritic branching | synaptic plasticity | cognition | antidepressant | anxiolytic

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Size Unit Price Stock
10 mg €105.00 In Stock
50 mg €365.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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