Based on 16 reference(s) in Google Scholar 8 10 16

Axon 2690

CAS [845714-00-3]

MF C12H11N3O
MW 213.24

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO



PHA-767491 is an ATP mimetic dual CDC7/CDK9 kinase inhibitor (IC50 values of 10 nM and 34 nM for CDC7 and CDK9, respectively). Treatment with PHA-767491 results in apoptotic cell death in multiple cancer cell types and tumor growth inhibition in preclinical cancer models. PHA-767491 is also a potent kinase inhibitor of MAPKAP-K2 (or MK-2) (IC50 value of 171 nM).

KEYWORDS: PHA-767491 | supplier | CDC7/CDK9 inhibitor | PHA767491 | PHA 767491 | CAS [845714-00-3] | DNA-RNA | CDC7 | CDK9 | Inhibitor | Enzymes | [942425-68-5] | MK-2 | MAPKAPK2

Size Unit Price Stock
10 mg €95.00 In Stock
50 mg €335.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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