LRE1 - RU-0204277

Based on 13 reference(s) in Google Scholar 8 10 13

Axon 2664

CAS [1252362-53-0]

MF C12H13ClN4S
MW 280.78

  • Purity: 98%
  • Soluble in DMSO



LRE1 is an allosteric soluble adenylyl cyclase (sAC)-specific inhibitor (IC50 value ≤ 10μM). Inhibition occurs by occupying the binding site of the physiological activator HCO3-, preventing sAC-dependent processes in cellular and physiological systems. LRE1 also inhibited cAMP accumulation in 4-4 cells (IC50 value 11 μM). Overall, this sAC inhibitor combines high potency and selectivity with stability, solubility and lack of cytotoxicity.

KEYWORDS: LRE1 | Allosteric sAC inhibitor | supplier | RU-0204277 | LRE 1 | LRE-1 | RU 0204277  | RU0204277  | CAS [1252362-53-0] | ATP | Adenylate cyclase | Inhibitor | Enzymes

Size Unit Price Stock
10 mg €95.00 In Stock
50 mg €345.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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