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Featured Products
Axon 2445
CAS [723249-01-2]
MF C13H13BrN2OSMW 325.22
Allosteric activator of AMP-activated protein kinase (AMPK; EC50 values 0.42 µM and 0.95 µM for increasing the activity of activated heterotrimers α1β1γ1 and α2β1γ1, respectively) that has no effect on mitochondrial function or the ADP/ATP ratio, and which exerts beneficial metabolic effects in vitro and in vivo. ZLN 024 reduced glucose intolerance and fatty liver characteristics in diabetic db/db mice and provides a promising therapeutic approach for type 2 diabetes mellitus and metabolic syndrome.
2-(2-(2-bromo-4-methylphenoxy)ethylthio)pyrimidine
[723249-01-2]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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