AZD 9291 - Osimertinib

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2342

CAS [1421373-65-0]

MF C28H33N7O2
MW 499.61

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

AZD 9291

Description

A potent oral, third-generation EGFR TKI, that irreversibly and selectively targets both sensitizing and resistant T790M+ mutant EGFR while harboring less activity toward wild-type EGFR (IC50 values 1 nM,12 nM, 5 nM, and 184 nM against L858R/T790M-, L858R-, L861Q-mutant, and WT EGFR, respectively).

KEYWORDS: AZD 9291 | supplier | EGFR inhibitor | Osimertinib | AZD9291 | CAS [1421373-65-0] | EGF | EGFR | Non-small cell lung cancer | NSCLC | ERBB | HER | T790M | TKI | cancer | oncology

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Size Unit Price Stock
10 mg €95.00 In Stock
50 mg €285.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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