R 55 - NSC 55712 | TPT 260 dihydrochloride |

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2303

CAS [2076-91-7]

MF C8H14Cl2N4S3
MW 333.32

  • Purity: 98%
  • Soluble in water and DMSO

R 55

Description

Retromer stabilizing pharmacological chaperone (Kd value ~5 μM) that binds at the Vps29 and Vps35 interface, and reduces Aβ peptide accumulation (IC50 value ~12 µM) and the pathogenic pathway of APP; useful pharmacological tool for research on Alzheimer's disease.
Thiophene derivative R55 was originally tested and proved active for its anticancer activity against Yoshida sarcoma.

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Size Unit Price Stock
10 mg €95.00 In Stock
50 mg €335.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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