BIBR 1532

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2301

CAS [321674-73-1]

MF C21H17NO3
MW 331.36

  • Purity: 99%
  • Soluble in DMSO

BIBR 1532

Description

Potent and selective inhibitor of native and recombinant human telomerase (IC50 values of ca. 100 nM), capable of inducing senescence in human cancer cells. BIBR1532 is a mixed-type non-competitive inhibitor of the human telomerase reverse transcriptase and human telomerase RNA components with similar potency primarily by interfering with the processivity of the enzyme.BIBR 1532 defines a novel class of mixed-type non-competitive telomerase inhibitor with mechanistic similarities to non-nucleosidic inhibitors of HIV1 reverse transcriptase.
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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