Remodelin

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2299

CAS [949912-58-7]

MF C15H14N4S
MW 282.36

  • Purity: 99%
  • Soluble in DMSO

Remodelin

Description

Potent Acetyl-transferase NAT 10 inhibitor that mediates nuclear shape rescue in laminopathic (LMNA-depleted) cells via microtubule reorganization. Remodelin markedly reduced the prevalence of misshapen nuclei in HGPS cells as well as in primary MRC5 fibroblasts aged in culture. In contrast, Remodelin had no effect on nonlaminopathic Werner syndrome cells
Potent NAT 10 inhibitor that mediates nuclear shape rescue in laminopathic cells via microtubule reorganization

Chemical name

4-(2-(2-cyclopentylidenehydrazinyl)thiazol-4-yl)benzonitrile

Parent CAS No.

[949912-58-7]

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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