SB 674042

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 2192

CAS [483313-22-0]

MW 448.51

  • Purity: 99%
  • Optical purity: >99% ee
  • Soluble in DMSO and Ethanol

SB 674042


Nonpeptide OX1 selective antagonist (Kd value 3.76 nM) with >100 fold selectivity over the OX2 receptor. SB 674042 displays no significant affinity for a range of serotonergic, dopaminergic, adrenergic and purinergic receptors at concentrations up to 10 μM. SB 674042 was also shown to be a competitive, functional antagonist of the OX1 receptor in the calcium mobilisation assay using CHO-DG44_OX1 cell lines.
Size Unit Price Stock
5 mg €99.00 In Stock
25 mg €350.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €160.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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