Your cart

There are no items in your shopping cart

SB 674042

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 2192

CAS [483313-22-0]

MF C24H21FN4O2S
MW 448.51

  • Purity: 99%
  • Optical purity: >99% ee
  • Soluble in DMSO and Ethanol

SB 674042

Description

Nonpeptide OX1 selective antagonist (Kd value 3.76 nM) with >100 fold selectivity over the OX2 receptor. SB 674042 displays no significant affinity for a range of serotonergic, dopaminergic, adrenergic and purinergic receptors at concentrations up to 10 μM. SB 674042 was also shown to be a competitive, functional antagonist of the OX1 receptor in the calcium mobilisation assay using CHO-DG44_OX1 cell lines.
Order
Size Unit Price Stock
5 mg €99.00 In Stock
25 mg €350.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €160.00 In Stock
Need more? Bulk Inquiry

Related Products

Axon ID Name Description From price
2012 EMPA Orexin type 2 (OX2) receptor antagonist €135.00
2095 SB 334867 First selective orexin 1 (OX1) antagonist €90.00
2744 TCS1102 Dual orexin (OX1/2) receptor antagonist €90.00
3805 MK-3697 Potent and selective Orexin receptor antagonist Inquire

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Newsletter
Give Feedback
 
Send E-mail

Customer Support

About Axon Medchem

Download Product Catalog

Download the Axon Ligands™ catalogue 2021 Spring Edition

Follow Us

© 2016 Axon Medchem. All Rights Reserved.

Send us a message

×

Contact Us

* Required Fields

Please wait...