SF 1670

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 2186

CAS [345630-40-2]

MF C19H17NO3
MW 307.34

  • Purity: 98%
  • Soluble in DMSO

SF 1670


Inhibitor of phosphatase and tensin homologue deleted on chromosome 10 (PTEN, IC50 value 2 µM), an important regulator of insulin-dependent signaling, that augments the efficacy of granulocyte transfusion in a clinically relevant mouse model. SF 1670 enhances neutrophil functions and fMLP-induced PtdIns(3,4,5)P3 signaling in neutrophils. SF 1670 is also a potent inhibitor of protein tyrosine phosphatase (PTP) CD45 (aka PTPRC; IC50 values 0.2 µM and 0.1 µM for CD45 induced pNPP hydrolysis and T-cell proliferation, respectively) and of galactokinase (GALK, IC50 value 0.7 µM).
Size Unit Price Stock
10 mg €120.00 In Stock
50 mg €450.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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