Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2185

CAS [331244-89-4]

MF C21H19N5O2S
MW 405.47

  • Purity: 98%
  • Soluble in DMSO



Selective small-molecule activator of proapoptotic BAX (IC50 value 3.3 μM) that binds to the BH3 binding domain without interacting with other BH3-binding pockets of antiapoptotic proteins or proapoptotic BAK. BAM 7 triggers in vitro BAX oligomerization, BAX-mediated pore formation and BAX-dependent cell death.
Size Unit Price Stock
10 mg €90.00 In Stock
50 mg €360.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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