Z-VAD-FMK - Z-VAD(OMe)-FMK

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2159

CAS [187389-52-2]

MF C22H30FN3O7
MW 467.49

  • Purity: 98%
  • Optical purity: Optically pure
  • Soluble in DMSO

Z-VAD-FMK

Description

Pan-caspase inhibitor with in vivo activity (Ki values 18.4 μM, 0.45 μM, and 17.1 μM for Caspase-3, -8, and -9 resp). Z-VAD-FMK inhibits apoptosis by blocking the processing of CPP32, and in pyrogallol-treated lung cancer Calu-6 cells via the prevention of GSH depletion. Z-VAD-FMK is a key compound for studies on apoptosis.

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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