Valdecoxib - SC 65872 | Bextra

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2106

CAS [181695-72-7]

MF C16H14N2O3S
MW 314.36

  • Purity: 99%
  • Soluble in DMSO

Valdecoxib

Description

NSAID. Highly selective and potent inhibitor of COX-2 in human whole blood and against the recombinant human enzyme, showing exceptional potency after oral administration. Valdecoxib showed weak inhibitory activity against COX-1 (IC50 = 140 µM), and potent activity against COX-2 (IC50 = 0.005 µM)
Selecive COX-2 inhibitor

Chemical name

4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide

Source information

Pfizer compound; Sold for research purposes under agreement from Pfizer Inc.

Parent CAS No.

[181695-72-7]

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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