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Enzymes
Transferases
Acyltransferases
HHAT
RU-SKI 43 hydrochloride

RU-SKI 43 hydrochloride

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2035

CAS [1782573-67-4]

MF C22H30N2O2S.HCl
MW 423.01

Purity: 99%
Soluble in DMSO

RU-SKI 43 hydrochloride

Description

Hedgehog acyltransferase (HHAT) inhibitor in vitro and in cells; it blocks sonic hedgehog (Shh) signaling significantly.

KEYWORDS: RU-SKI 43 hydrochloride | Supplier | HHAT inhibitor | RU-SKI43 | RUSKI-43 | RUSKI43 | CAS [1782573-67-4] | [1043797-53-0] | Sonic hedgehog | HHAT | Inhibitor | Enzymes

E Petrova et al. Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling. Nature Chem. Biol. 2013, 9, 247–249.

E Petrova et al. Hedgehog acyltransferase as a target in pancreatic ductal adenocarcinoma. Oncogene. 2015 Jan 8;34(2):263-8.

Cell Signaling & Oncology CNS Stem Cell HHAT Hedgehog EC 2.3.1

Hedgehog acyltransferase (HHAT) inhibitor blocks Shh signaling

Chemical name

2-(2-methylbutylamino)-1-(4-(m-tolyloxymethyl)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanone hydrochloride

Parent CAS No.

[1043797-53-0]

Order

Size	Unit Price	Stock
5 mg	€110.00	In Stock
25 mg	€390.00	In Stock

Special Offers

Size	Unit Price	Stock
2 x 5 mg	€180.00	In Stock
2 x 25 mg	€620.00	In Stock

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