R 547

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1983

CAS [741713-40-6]

MF C18H21F2N5O4S
MW 441.45

  • Purity: 99%
  • Soluble in DMSO

R 547


Potent and selective CDK inhibitor with Ki values to be 1, 3, 1 nM for CDK1, CDK2, and CDK4 respectively; inactive (Ki >5000 nM) against a panel of >120 unrelated kinases. R547 effectively inhibits proliferation of tumor cell lines independent of multidrug resistant status, histologic type, retinoblastoma protein, or p53 status, with IC50 values smaller or equal to 0.60 µM in vitro.
Size Unit Price Stock
5 mg €95.00 In Stock
25 mg €285.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €140.00 In Stock
2 x 25 mg €440.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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