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Axon 1950
CAS [218600-44-3]
MF C31H41NO4MW 491.66
A potent multifunctional anti-tumor agent; CDDO induces apoptosis in vitro in malignant cells through both intrinsic and extrinsic pathways, and it controls cellular differentiation, apoptosis, and growth inhibition by serving as a ligand for the transcription factor PPAR-γ; highly active inhibitor of nitric oxide production in mouse macrophages; it shows antiinflammatory activity against thioglycollate-interferon-gamma-induced mouse peritonitis
* Parent acid of CDDO-Me (Axon 1772)
(4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicene-4a-carboxylic acid
[218600-44-3]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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