CP 316819

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1847

CAS [186392-43-8]

MF C21H22ClN3O4
MW 415.87

Purity: 99%
Optical purity: Optically pure
Soluble in DMSO

CP 316819

Description

Potent glycogen phosphorylase (GPase) inhibitor (IC50: 40 nM against human liver GPα). CP-316819 facilitates glycogen utilization in the brain, prevents neuronal cell death and maintains brain electrical currents

SW Suh et al. Astrocyte glycogen sustains neuronal activity during hypoglycemia: studies with the glycogen phosphorylase inhibitor CP-316,819 ([R-R*,S*]-5-chloro-N-[2-hydroxy-3-(...). J. Pharmacol. Exp. Ther. 2007, 1, 45-50.

DG Baker et al. Glycogen phosphorylase inhibition in type 2 diabetes therapy: a systematic evaluation of metabolic and functional effects in rat skeletal muscle. Diabetes 2005, 54, 2453.

Glycogen Phosphorylase (GPase) inhibitor

Chemical name

5-chloro-N-((2S,3R)-3-hydroxy-4-(methoxy(methyl)amino)-4-oxo-1-phenylbutan-2-yl)-1H-indole-2-carboxamide

Parent CAS No.

[186392-43-8]

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CP 316819

Description

Chemical name

Parent CAS No.

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CP 316819

Description

Chemical name

Parent CAS No.

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