BH3I 1 - BHI 1

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1828

CAS [300817-68-9]

MF C15H14BrNO3S2
MW 400.31

Purity: 99%
Soluble in 0.1N NaOH(aq) and DMSO

BH3I 1

Description

Cell permeable antitumor agent targeting Bcl-2 family protein, more specifically as Bcl-xL antagonist; apoptosis inducer, inducing a dose- and time-dependent apoptosis in H460 and H1792 cells

W Roa et al. Enhancement of radiation sensitivity with BH3I-1 in non-small cell lung cancer. Clin. Invest. Med. 2005, 28(2), 55-63.

S Shangary and DE Johnson. Recent advances in the development of anticancer agents targeting cell death inhibitors in the Bcl-2 protein family. Leukemia 2003, 17, 1470–1481.

Inhibitor of Bcl-2 family protein

Chemical name

2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)-3-methylbutanoic acid

Parent CAS No.

[300817-68-9]

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10 mg	€125.00	In Stock
50 mg	€425.00	In Stock

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BH3I 1 - BHI 1

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Description

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