Erastin

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1825

CAS [571203-78-6]

MF C30H31ClN4O4
MW 547.04

  • Purity: 99%
  • Soluble in DMSO

Erastin

Description

An anti-tumor agent with RAS-selective lethality. Erastin binds to mitochondrial voltage-dependent anion channels (VDAC) proteins, more specifically on VDAC2 and alters its gating; induce non-apoptotic cell death selectively in some tumour cells harbouring activating mutations in the RAS-RAF-MEK pathway
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Size Unit Price Stock
5 mg €95.00 In Stock
10 mg €135.00 In Stock
50 mg €535.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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