Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1825

CAS [571203-78-6]

MF C30H31ClN4O4
MW 547.04

  • Purity: 99%
  • Soluble in DMSO



An anti-tumor agent with RAS-selective lethality. Erastin binds to mitochondrial voltage-dependent anion channels (VDAC) proteins, more specifically on VDAC2 and alters its gating; induce non-apoptotic cell death selectively in some tumour cells harbouring activating mutations in the RAS-RAF-MEK pathway
Size Unit Price Stock
5 mg €90.00 In Stock
10 mg €130.00 In Stock
50 mg €460.00 In Stock
Need more? Bulk Inquiry

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...