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Axon 1734
CAS [343240-54-0]
MF C15H13Cl2N3O2MW 338.19
Building block for synthesis of dihydropyrazolopyrimidine inhibitors of Kv1.5 (IKur). The ethylester analog of inhibitor 1734 is a modest inhibitor itself (IC50 value 1.1 µM for human Kv1.5), but exhibiting encouraging KV1.5 versus L-type calcium channel selectivity.
KEYWORDS: K+ Channel inhibitor 1734 | supplier | Building block | CAS [343240-54-0] | [1026960-80-4] | Potassium | Kv1.5 | Ikur | BMS | L-type | calcium channel
methyl 7-(2,3-dichlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate
[343240-54-0]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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