SGI 1776 free base

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1633

CAS [1025065-69-3]

MF C20H22F3N5O
MW 405.42

  • Purity: 98%
  • Soluble in 0.1N HCl(aq) and DMSO

SGI 1776 free base

Description

A potent and selective inhibitor of Pim kinases, inducing apoptosis and cell cycle arrest, thereby causing a reduction in phospho-BAD levels and enhancement of mTOR inhibition in vitro. Most notably, SGI-1776 induced significant tumor regression in MV-4-11 (AML) and MOLM-13 (AML) xenograft models
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5 mg €95.00 In Stock
25 mg €325.00 In Stock
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2 x 5 mg €140.00 In Stock
2 x 25 mg €480.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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