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Featured Products
Axon 1610
CAS [915720-21-7]
MF C17H19ClFN7OMW 391.83
Potent and selective tyrosine kinase (Trk) inhibitor with IC50 to 2 and 8 nM for TrkA and TrkB respectively; AZ-23 showed in vivo TrkA kinase inhibition and efficacy in mice following oral administration; having potential for therapeutic utility in neuroblastoma and multiple other cancer indications.
KEYWORDS: AZ 23 | supplier | TrkA inhibitor | AZ23 |CAS[915720-21-7] | Neurotrophin | Trk | Inhibitor | tyrosine kinase | TrkA | TrkB | neuroblastoma | cancer
(S)-5-chloro-N2-(1-(5-fluoropyridin-2-yl)ethyl)-N4-(5-isopropoxy-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
[915720-21-7]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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