OSI 930

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1547

CAS [728033-96-3]

MF C22H16F3N3O2S
MW 443.44

Purity: 99%
Soluble in DMSO

OSI 930

Description

A potent and orally active inhibitor of tyrosine kinases, targeting c-KIT and VEGFR2; OSI-930 is designed to target both cancer cell proliferation and blood vessel growth (angiogenesis) in selected tumors

AJ Garton et al. OSI-930: A Novel Selective Inhibitor of Kit and Kinase Insert Domain Receptor Tyrosine Kinases with Antitumor Activity in Mouse Xenograft Models. Cancer Res 2006, 66(2), 1015-1024.

Angiogenesis Cell Signaling & Oncology VEGFR c-KIT RTK class III and IV; EC 2.7.10.1

c-Kit and VEGFR2 tyrosine kinase inhibitor

Chemical name

3-(quinolin-4-ylmethylamino)-N-(4-(trifluoromethoxy)phenyl)thiophene-2-carboxamide

Parent CAS No.

[728033-96-3]

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Size	Unit Price	Stock
5 mg	€90.00	In Stock
25 mg	€320.00	In Stock

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Size	Unit Price	Stock
2 x 5 mg	€140.00	In Stock
2 x 25 mg	€480.00	In Stock

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