Seratrodast - AA 2414

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1447

CAS [112665-43-7]

MF C22H26O4
MW 354.44

Purity: 99%
Soluble in 0.1N NaOH(aq) and DMSO

Seratrodast

Description

Thromboxane A2 (TP) receptor antagonist used in the treatment of asthma

S Endo and K Akiyama. Thromboxane A2 receptor antagonist in asthma therapy (in Japanese). Nippon Rinsho 54 (11): 3045–8.

S Hada et al. Study on the inhibitory effect of AA-2414 on platelet aggregation and its clinical effect in asthmatic patients (in Japanese). Arerugi 42 (1): 18–25.

Kurokawa et al. Antagonism of the human thromboxane A2 receptor by an anti-asthmatic agent AA-2414. Biol.Pharm.Bull. 1994, 17, 383.

Thromboxane A2 antagonist

Chemical name

7-Phenyl-7-(2,4,5-trimethyl-3,6-dioxo-cyclohexa-1,4-dienyl)-heptanoic acid

Parent CAS No.

[112665-43-7]

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