GMC 1-109

Based on 4 reference(s) in Google Scholar 8 10 4

Axon 1289

CAS [183140-96-7]

MF C19H19F3N4O3S
MW 440.44

GMC 1-109

Description

Analogue of clozapine (Axon 1146); devoid of DA, 5-HT2, H1 and α1 affinities, but with high M1 affinity (IC50 value of 35 nM).

CNS CHRM1 A18

Clozapine analog devoid of DA, 5-HT2, H1 and α1 affinities, but with high M1 affinity

11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-8-yl trifluoromethanesulfonate

[183140-96-7]

Order

Size	Unit Price	Stock
5 mg	€125.00	In Stock
25 mg	€425.00	In Stock

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Axon ID	Name	Description
1146	Clozapine	Atypical antipsychotic	€50.00
1147	Isoclozapine	Typical antipsychotic	€135.00
1149	GMC 61-39	Atypical antipsychotic	Inquire
1151	GMC 1-116	Clozapine analogue	€125.00
1152	GMC 1-165	Clozapine analog with 5-HT2A and M1 affinity, devoid of D1/D2 affinities	€135.00
1298	Olanzapine	Atypical antipsychotic	€75.00
1703	VU 0357017 hydrochloride	PAM of M1 mAChR	€115.00
1787	VU 0255035	Selective M1 mAChR Antagonist	€120.00
2049	Tolterodine L-tartrate	Muscarinic receptor (mAChR) antagonist	€60.00
1988	VU 0029767	PAM of mAChR M1 that potentiates the agonistic effect of Ach	€110.00
2463	TBPB	Allosteric activator of the M1 acetylcholine receptor devoid of M2-M5 activity.	€105.00
2851	GMC 1-161	Clozapine analog with 5-HT2A, M1 and D2 affinity, devoid of D1 affinities	€135.00
2846	N-Desmethylclozapine	Metabolite of Clozapine	€90.00
2796	Clozapine N-oxide	Muscarinic DREADD agonist	€95.00
3271	VU0486846	Potent and highly selective PAM of M1 mAChR	€165.00
3286	Penehyclidine hydrochloride	Anticholinergic drug	€130.00
3505	Oxybutynin hydrochloride	Competitive M1/M2/M3 mAChR antagonist	€50.00
3513	Bethanechol chloride	Muscarinic receptor (mAChR) agonist	€50.00
3648	Trospium chloride	Specific, orally active and competitive muscarinic receptor (mAChR) antagonist	€60.00