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Receptors
Unclassified
PB28 dihydrochloride

PB28 dihydrochloride

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1272

CAS [172907-03-8]

MF C24H38N2O.2HCl
MW 443.49

Purity: 99%
Soluble in water

PB28 dihydrochloride

Description

High affinity sigma-2 agonist

G Cassano et al. The sigma-2 receptor agonist PB28 inhibits calcium release from the endoplasmic reticulum of SK-N-SH neuroblastoma cells. Cell Calcium 2006, 40(1), 23-28.

A Azzariti et al. Cyclohexylpiperazine derivative PB28, a sigma2 agonist and sigma1 antagonist receptor, inhibits cell growth, modulates P-glycoprotein, and synergizes with anthracyclines in breast cancer. Mol. Cancer Ther. 2006, 5(7), 1807-1816.

Cell Signaling & Oncology Sigma Unclassified

Sigma-2 agonist

Chemical name

1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine dihydrochloride

Parent CAS No.

[172906-90-0]

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Size	Unit Price	Stock
10 mg	€85.00	In Stock
50 mg	€320.00	In Stock

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