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Axon 1247
CAS [15923-42-9]
MF C13H16N2.HClMW 236.74
Potent 5-HT2 ligand (Ki values 18 nM, 18 nM, and 66 nM for 5-HT2A, 5-HT2C, and 5-HT2B, respectively). PNU 22394 is virtually a full agonist at 5-HT2C receptors (87% of 5-HT), but a partial agonist at 5-HT2A (65% of 5-HT), and 5-HT2B (<15% of 5-HT) receptors, and produced a dose-related decrease in food consumption compared to saline-treated control rats.
KEYWORDS: PNU 22394 hydrochloride | supplier | 5-HT2C agonist | PNU22394 | PNU 22394A | CAS [15923-42-9] | [15923-78-1] | Serotonin | 5-HT2C | Agonist | 5-HT2A | 5-HT2B | food | consumption | obesity | weight loss | metabolism | hypophagic | anorexogenic
6-Methyl-1,2,3,4,5,6-hexahydro-azepino[4,5-b]indole hydrochloride
[15923-78-1]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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