(+)-MDL 105725 - MDL 105725

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1107

CAS [189192-18-5]

MF C21H26FNO3
MW 359.43

(+)-MDL 105725

Description

Active metabolite of MDL 100907 (Axon 1104), a selective 5-HT2A antagonist; Precursor for [¹¹C]MDL100907.

Both the racemate (±)-MDL 105725 (Axon 1106) and less active enantiomer (-)-MDL 105725 (Axon 1108) are available as well.

CNS 5-HT2A A17

5-HT2A antagonist

3-((R)-{1-[2-(4-Fluoro-phenyl)-ethyl]-piperidin-4-yl}-hydroxy-methyl)-2-methoxy-phenol

[189192-18-5]

Axon ID	Name	Description
1102	Nefazodone hydrochloride	Antidepressant; 5-HT2A antagonist	€85.00
1103	MDL 100151	5-HT2A antagonist	€110.00
1104	MDL 100907	5-HT2A antagonist	€110.00
1105	MDL 100009	5-HT2A antagonist	€125.00
1106	(±)-MDL 105725	5-HT2A antagonist	€210.00
1108	(-)-MDL 105725	5-HT2A antagonist	Inquire
1118	RO 60-0175	5-HT2C agonist	€140.00
1141	Sertindole	5-HT2, D2 and α1 adrenoceptor antagonist	€82.00
1214	MK 212 hydrochloride	5-HT2C agonist	€75.00
1247	PNU 22394 hydrochloride	Potent 5-HT ligand with full agonistic properties for 5-HT2C	€90.00
1439	Eplivanserin	5-HT2A antagonist/inverse agonist	€80.00
1450	Ketanserin	5-HT2A antagonist	€55.00
1745	SB 242084 hydrochloride	Selective 5-HT2C receptor antagonist	€110.00
2127	Fluphenazine decanoate dihydrochloride	Antipsychotic with high affinity for dopamine and serotonin receptors	€60.00
2811	25CN-NBOH hydrochloride	Selective brain penetrant 5-HT2A receptor agonist	€150.00
3511	Cyproheptadine hydrochloride	5-HT2A and H1 antagonist	€50.00
3859	Roluperidone	Sigma-2 and 5-HT2A receptor antagonist	€120.00
3925	IHCH-7079	5-HT2A receptor arrestin-biased agonist	€150.00
4092	SB 242084	Selective 5-HT2C receptor antagonist	€110.00