(S)-5-Hydroxy-DPAT hydrobromide - (S)-5-OH-DPAT

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1008

CAS [182210-74-8]

MF C16H25NO.HBr
MW 328.29

Purity: 98%
Optical purity: >98% ee
Soluble in DMSO

(S)-5-Hydroxy-DPAT hydrobromide

Description

Potent and selective dopamine (DA) D2-receptor agonist; more active (S)- enantiomer of 5-OH-DPAT (Axon 1006); its opposite enantiomer, R-5-OH-DPAT (Axon 1007), is a weakly potent D2 antagonist

A. Karlsson et al. (R)- and (S)-5-hydroxy-2-(dipropylamino)tetralin (5-OH DPAT): Assessment of optical purities and dopaminergic activities. Chirality. 1989-1995, 2(2), 90-95.

B Shi et al. Radiosynthesis and in vitro evaluation of 2-(N-alkyl-N-1'-11C-propyl)amino-5-hydroxytetralin analogs as high affinity agonists for dopamine D-2 receptors.Nucl Med Biol. 1999, 26(7), 725-35. (PubMed)

J Mukherjee et al. In vitro and in vivo evaluation of the binding of the dopamine D2 receptor agonist (11)C-(R,S)-5-hydroxy-2-(di-n-propylamino)tetralin in rodents and nonhuman primate.Synapse. 2000, 37(1), 64-70. (PubMed)

CNS D2 A17

D2 agonist

Chemical name

(S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol hydrobromide

Parent CAS No.

[68643-08-3]

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5 mg	€145.00	In Stock

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(S)-5-Hydroxy-DPAT hydrobromide - (S)-5-OH-DPAT

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Parent CAS No.

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(S)-5-Hydroxy-DPAT hydrobromide - (S)-5-OH-DPAT

Description

Chemical name

Parent CAS No.

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