Matrix

Cellular matrices embed specialized molecular structures that typically provide structural and biochemical support to the surroundings. This section is lists pharmacologically active compounds that influence the formation of e.g. microtubules or affect cell-cell adhesion interactions, among many others. Individual sections are created for Axon Ligands™ that affect the extracellular matrix, and ligands that interfere with molecular structures within cells.

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Axon ID Name Description From price
2552 Adjudin Non-hormonal male contraceptive with anti-proliferative activity €125.00
3748 C-82 Specific inhibitor of Wnt/β-catenin signaling pathway €110.00
1442 Caprospinol Alzheimer's disease therapeutic and antihistaminergic drug €110.00
2161 CCT 031374 hydrobromide Inhibitor of TCF-dependent transcription of genes of Wnt signaling pathway €60.00
2916 Cevipabulin Potent microtubule-active antitumor agent €140.00
3243 CK-666 Arp2/3 complex inhibitor €100.00
3371 Colchicine Tubulin polymerization inhibitor €50.00
1233 Combretastatin-A4 Tubulin polymerization inhibitor €85.00
3715 E-7386 CBP/beta-catenin modulator Inquire
1443 Genipin Protein cross-linker; stimulates insulin secretion €55.00
1650 HTI 286 Tubulin polymerization inhibitor €140.00
1766 ICG 001 Specific inhibitor of Wnt/β-catenin signaling pathway €115.00
2135 iCRT14 Small-molecule inhibitor of the Wnt/wingless signaling pathway; CRT inhibitor €135.00
2133 iCRT5 β-Catenin-responsive transcription (CRT) inhibitor €80.00
2406 IMM 01 Small-molecule agonist of mammalian Diaphanous (mDia)-related formins €95.00
3948 ISX9 Wnt/β-catenin signaling pathway agonist €110.00
2378 Kartogenin Promotor of chondrocyte differentiation from primary human MSCs €75.00
2869 LX2343 BACE 1 inhibitor €125.00
2658 MPT0B098 Microtubule inhibitor that suppresses JAK2/STAT3 signaling €105.00
3342 MSAB Potent and selective inhibitor of Wnt/β-catenin signaling pathway €80.00
1310 Myoseverin Tubulin polymerization inhibitor €125.00
2332 OTX 008 Selective allosteric inhibitor of galectin-1 €125.00
3152 PAWI-2 Inhibitor which targets both Wnt signaling and ATM/p53 €120.00
3368 Podophyllotoxin Tubulin polymerization inhibitor €40.00
3749 PRI-724 Specific inhibitor of Wnt/β-catenin signaling pathway €190.00
3746 PTI-125 dihydrochloride Orally available molecule targeting filamin A (FLNA) €120.00
3083 PVHD121 Microtubule inhibitor €120.00
3804 Sabizabulin Orally bioavailable and highly potent tubulin polymerization inhibitor €220.00
2084 SKL 2001 Wnt/β-catenin signaling pathway agonist or activator €90.00
2481 SMT C1100 Orally active, non-toxic upregulator of utrophin production €125.00

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