Oxidoreductases
Oxidoreductases (EC 1.) comprise the large class of enzymes that catalyze biological oxidation/reduction reactions. They play an important role in both aerobic and anaerobic metabolism. They can be found in glycolysis, TCA cycle, oxidative phosphorylation, and in amino acid metabolism. Subcategories within this class of biological targets are created based the kind of acceptor molecules involved in the redox reaction they catalyze, and on and the nature of their substrates[1].
[1] Enzyme Nomenclature 1992. Academic Press,San Diego,California, ISBN 0-12-227164-5.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1066 | N-Cyclopropyl-N-methyl-2-aminotetraline hydrobromide | MAO inhibitor | €95.00 | |
| 2989 | 15-LOX-1 inhibitor i472 | Inhibitor of 15-lipoxygenase-1 (15-LOX-1) | €170.00 | |
| 1873 | Abiraterone | Inhibitor of CYP17A1 | €90.00 | |
| 1874 | Abiraterone acetate | Prodrug of Abiraterone; Inhibitor of CYP17A1 | €90.00 | |
| 2746 | AG-120 | IDH1 mutant enzyme inhibitor | €125.00 | |
| 2745 | AG-221 | IDH2 mutant enzyme inhibitor | €95.00 | |
| 2122 | AGI 5198 | Inhibitor of R132 mutant isocitrate dehydrogenase 1 (IDH1) | €60.00 | |
| 2274 | AGI 6780 | Potent and selective inhibitor of the tumor-associated mutant IDH2 (R140Q) | €90.00 | |
| 2551 | Alda 1 | Small molecule activator of ALDH2 | €65.00 | |
| 3316 | Anastrozole | Potent, highly selective, and orally active aromatase inhibitor | €50.00 | |
| 2883 | APPA | Aldose reductase inhibitor | €105.00 | |
| 2819 | APX-115 | First-in-class pan-NADPH oxidase (Nox) inhibitor | €125.00 | |
| 2787 | ASP 9521 | Inhibitor of 17 β–hydroxysteroid dehydrogenase type 5 | €75.00 | |
| 2288 | ATB 346 | Orally active hydrogen sulfide-releasing cyclooxygenase inhibitor | €110.00 | |
| 2043 | Atorvastatin calcium | Inhibitor of HMG-CoA reductase | €60.00 | |
| 3943 | AVN944 | Incompetitive small molecule inhibitor of inosine monophosphate dehydrogenase (IMPDH) | Inquire | |
| 3863 | BAY-1436032 | Highly selective, potent and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1) | Inquire | |
| 3638 | BAY-179 | Potent, selective, and species cross-reactive complex I inhibitor | €100.00 | |
| 2306 | Bizine | Potent LSD1 inhibitor with selectivity over MAO-A/B, and LSD2 | €120.00 | |
| 3479 | BN80933 | Potent antioxidant and selective nNOS inhibitor | €150.00 | |
| 2489 | Brassinin | Dual IDO1/STAT3 inhibitor with antifungal and anticancer activity | €75.00 | |
| 2698 | BTZ043 | Antimycobacterial DprE1 inhibitor that kills Mycobacterium tuberculosis | €105.00 | |
| 1756 | BVT 2733 hydrochloride | Inhibitor of 11β-hydroxysteroid dehydrogenase type 1 | €90.00 | |
| 2585 | CBR 5884 | Noncompetitive inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) | €90.00 | |
| 1919 | Celecoxib | Selective COX-2 inhibitor | €50.00 | |
| 3163 | Clotrimazole | Fungal CYP450 enzyme 14α-demethylase inhibitor | €50.00 | |
| 2622 | CPI 4203 | Selective inhibitor of KDM5 demethylases (H3K4 specific) | €85.00 | |
| 2573 | CPI 455 | Selective inhibitor of KDM5 demethylases (H3K4 specific) | €95.00 | |
| 2125 | CPI-613 | Inhibitor of mitochondrial pyruvate dehydrogenase (PDH) complex | €110.00 | |
| 3725 | CVT-10216 | Highly selective, reversible inhibitor of ALDH-2 | €110.00 | |