PEPCK

Cytosolic Phosphoenolpyruvate carboxykinase (cPEPCK; EC 4.1.1.32) is an enzyme in the lyase family used in the metabolic pathway of gluconeogenesis. It converts oxaloacetate into phosphoenolpyruvate and carbon dioxide. cPEPCK has become a virtual marker for hepatic gluconeogenesis, and the level of its gene transcription in the liver is considered an important indicator in the evaluation of type 2 diabetes[1].


[1] A Perspective on the Biology of Phosphoenolpyruvate Carboxykinase 55 Years After Its Discovery. R.W. Hanson. J. Biol. Chem.Them. Minirev. Ser. 2009, 1-6.

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1165 cPEPCK inhibitor cPEPCK inhibitor €145.00

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