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Axon 2566
CAS [1188890-40-5]
MF C26H29ClN2O4SMW 501.04
Inhibitor of multifunctional Ca2+/Calmodulin-dependent protein kinase (CaMKII; Ki value 0.37 μM for inhibition of CaMKII phosphorylating activity). In addition, KN93 also affects CaV1.3 and CaV1.2 calcium channels in a CaMKII-independent manner.
The water soluble phosphate salt of KN 93 (Axon 2555) is available as well.
KEYWORDS: KN 93 | supplier | CaMKII inhibitor | KN93 | CAS [1188890-40-5] | [1188890-41-6] | LCC | RyRs |PLB| CaMK | Inhibitor | calcium | channel | calmodulin | myosin | dependent | Ca2+ | CaV1.3 | CaV1.2 | Alzheimer’s | Angelman | L-type | ryanodine | phospholamban | ECC | arrhythmia
(E)-N-(2-(((3-(4-chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide
[1188890-40-5]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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