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Axon 2508
CAS [1253452-78-6]
MF C22H19N3O5MW 405.40
Inhibitor of the ABC-transporter Breast Cancer Resistance Protein (BCRP or ABCG2; IC50 value of 1.39 µM). KS 176 is ca 50-fold more potent than Novobiocin (IC50 value 65 µM), and nearly equipotent compared to KO 143 (Axon 1409), and does not show inhibition of P-gp and MRP1.
KEYWORDS: KS 176 | Supplier | BCRP inhibitor | Axon Medchem | Axon 2508 | KS176 | CAS [1253452-78-6] | [93129-94-3] | BCRP | Inhibitor | ABC | transporter | breast | cancer | resistance | protein | Novobiocin | KO143 | KO 143
N-[4-(2-hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]benzamide
[1253452-78-6]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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