Trelagliptin succinate - SYR 111472 succinate | SYR 472

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2470

CAS [1029877-94-8]

MF C18H20FN5O2.C4H6O4
MW 475.47

Purity: 100%
Optical purity: Optically pure
Soluble in water and DMSO

Trelagliptin succinate

Description

Orally active DPP-4 inhibitor that produces clinically and statistically significant improvements in glycaemic control in patients with type 2 diabetes. SYR472 has a long duration of action and is well tolerated in clinical studies.

N. Inagaki et al. SYR-472, a novel once-weekly dipeptidyl peptidase-4 (DPP-4) inhibitor, in type 2 diabetes mellitus: a phase 2, randomised, double-blind, placebo-controlled trial. Lancet Diabetes Endocrinol. 2014 Feb;2(2):125-32.

K. V. T. S. Pavan Kumar et al. Study of plant glucosylxanthone & its analogs, as DPPIV inhibitor for anti-diabetic activity. Int. J. Pharm. Sci. Rev. Res., 15(1), 2012, 17, 83-87.

A.J. Garber et al. The importance of incretin therapies for managing type 2 diabetes. Lancet Diabetes Endocrinol. 2014 Feb;2(2):95-7.

Orally active DPP4 inhibitor for the treatment of type 2 diabetes

Chemical name

(R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile succinate

Parent CAS No.

[865759-25-7]

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10 mg	€145.00	In Stock
50 mg	€505.00	In Stock

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Trelagliptin succinate - SYR 111472 succinate | SYR 472

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Trelagliptin succinate - SYR 111472 succinate | SYR 472

Description

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Parent CAS No.

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