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ANA 12

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2468

CAS [219766-25-3]

MF C22H21N3O3S
MW 407.49

  • Purity: 100%
  • Soluble in DMSO

ANA 12

Description

Selective TrkB antagonist (IC50 value 45.6 ± 8.4 nM for the high-affinity TetOn-rhTrkB) with anxiolytic and antidepressant activity in mice that inhibits processes downstream of TrkB without altering TrkA and TrkC functions. A valuable tool for studying BDNF/TrkB signaling. ANA-12 is also capable of reversing the diminished self-administration of cocaine in male CocSired rats by means of enhanced BDNF expression.
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Size Unit Price Stock
5 mg €90.00 In Stock
25 mg €320.00 In Stock
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Size Unit Price Stock
2 x 5 mg €140.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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