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KY 05009

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 2395

CAS [1228280-29-2]

MF C18H16N4O2S
MW 352.41

  • Purity: 99%
  • Soluble in DMSO

KY 05009

Description

Inhibitor of Traf2- and Nck-Interacting Kinase (TNIK; Ki value 100 nM in ATP-competitive assay) that attenuates TGF-β1-mediated Wnt and Smad signaling and epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma A549 cells. Additionally, KY05009 inhibits TGF-β1-induced phosphorylation of JNK1/2, FAK, Src, and paxillin.
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Size Unit Price Stock
10 mg €125.00 In Stock
50 mg €425.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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