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Axon 2367
CAS [1228690-36-5]
MF C27H24N2O5MW 456.49
A novel potent and selective LPA1 antagonist (IC50 values 0.025 μM and 0.023 μM for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA1-transfected CHO cells,respectively). AM 095 attenuates bleomycin-induced dermal fibrosis.
(R)-2-(4'-(3-methyl-4-((1-phenylethoxy)carbonylamino)isoxazol-5-yl)biphenyl-4-yl)acetic acid
[1228690-36-5]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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