AZ 20

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2345

CAS [1233339-22-4]

MF C21H24N4O3S
MW 412.51

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in 0.1N HCl(aq) and DMSO

AZ 20

Description

Potent, orally active and selective inhibitor of ATR protein kinase with monotherapy in vivo antitumor activity (IC50 value 5 nM). AZ 20 potently inhibits the growth of LoVo colorectal adenocarcinoma tumor cells in vitro, and is a useful compound to explore ATR pharmacology in vivo.

KEYWORDS: AZ 20 | supplier | ATR inhibitor | AZ20 | AZ-20 | CAS [1233339-22-4] | DNA-damage response | ATR | ATM | DNA | damage control | cancer | oncology | Checkpoint | cell cycle control

Order
Size Unit Price Stock
5 mg €105.00 In Stock
25 mg €385.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €170.00 In Stock
2 x 25 mg €600.00 In Stock
Need more? Bulk Inquiry

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...