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Apoptozole

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2251

CAS [1054543-47-3]

MF C33H25F6N3O3
MW 625.56

  • Purity: 100%
  • Soluble in DMSO

Apoptozole

Description

An apoptosis-inducing small molecule that inhibits the ATPase activity of heat shock cognate 70 (Hsc70) and Hsp70 by binding to its ATPase domain (Kd values 0.21 and 0.14 μM for Hsc70 and Hsp70, respectively as determined by surface plasmon resonance (SPR) spectroscopy). Apoptozole has high cellular potency to restore the chloride channel activity of mutant CFTR by promoting its membrane trafficking.
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Size Unit Price Stock
10 mg €95.00 In Stock
50 mg €395.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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