Chemistry Service Platform - CRO in Medicinal Chemistry

Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

 

  

SC 66

 

 

CAS 871361-88-5

C18H18N2O MW 276.33

Purity: 99%

Soluble in DMSO to 100 mM

Soluble in EtOH to 100 mM

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1790    Prime Source

 

Qty1: 10 mg / €75  $98

Promotion: 2 x 10 mg @ €120  $156

Qty2: 50 mg / €225  $293

Promotion: 2 x 50 mg @ €360  $468

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

Contact us for payment and tech support.

 

Biological Activity:

 

An allosteric Akt inhibitor, targeting pleckstrin homology domain and facilitating Akt ubiquitination.

 

References:

 

J Hakryul et al. Deactivation of Akt by a small molecule inhibitor targeting pleckstrin homology domain and facilitating Akt ubiquitination. Proc. Natl. Acad. Sci. USA 2011, 108(16), 6486-6491. [online]

 

 

 

Chemical Name: (2E,6E)-2,6-bis(pyridin-4-ylmethylene)cyclohexanone

 

SC 66 | AKT inhibitor | Axon Medchem | Axon 1790 | SC66 

axonmedchem.com © 2012

 

Axon Ligands In The Field:

 

Perifosine | AKT inhibitor

MK 2206 | AKT inhibitor

GSK 690693 | AKT inhibitor

Deguelin | AKT inhibitor

SC 66 | AKT inhibitor

 

 

Click Here To See Featured Cell Signaling and Oncology Ligands from Axon Ligands Collection