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Biological Activity:
An allosteric Akt inhibitor, targeting pleckstrin homology domain and facilitating Akt ubiquitination.
References:
J Hakryul et al. Deactivation of Akt by a small molecule inhibitor targeting pleckstrin homology domain and facilitating Akt ubiquitination. Proc. Natl. Acad. Sci. USA 2011, 108(16), 6486-6491. [online]
Chemical Name: (2E,6E)-2,6-bis(pyridin-4-ylmethylene)cyclohexanone
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