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VU 0255035

CAS 1135243-19-4

C18H20N6O3S2  MW 432.52

Purity: 99%

Soluble in DMSO to 100 mM

Ordering Information:

Cat. No. Axon 1787   Prime Source

Qty1: 10 mg / €115  $150

Qty2: 50 mg / €435  $566 

Qty3: on request

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Biological Activity:   Hilghly selective antagonist of M1 muscarinic acetylcholine receptor (mAChR) (Ki=14.87 nM).   References:   DJ Sheffler et al. A novel selective muscarinic acetylcholine receptor subtype 1 antagonist reduces seizures without impairing hippocampus-dependent learning. Mol.Pharmacol. 2009, 76(2), 356-368. [online]        Chemical Name: N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide

VU 0255035 | M1 antagonist | Axon Medchem | Axon 1787 | VU0255035

Axon LigandsTM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Field:

VU 0255035 | M1 antagonist

MDL 201012 | M3 antagonist

Zamifenacin | M3 antagonist

VU 0238429 | M5 PAM