Chemistry Service Platform - CRO in Medicinal Chemistry

Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

  

MG 149

 

 

CAS 1243583-85-8

C22H28O3  MW 340.46

Purity: 99%

Soluble in DMSO to 100 mM

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1785     Exclusive

 

Qty1: 5mg €125  $163

 

Qty2: 25 mg / 425  $533

 

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

Contact us for payment and tech support.

Biological Activity:

 

A novel anacardic acid analog; potent and selective inhibitor of the MYST family (Tip60 and MOZ) of histone acetyltransferase (HAT). In addition, it effectively inhibits acetyltransferase activity of HeLa cells nuclear extracts.

 

References:

 

M. Ghizzoni et al. 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. Eur. J. Med. Chem. 2012, 47(1), 337-344. [online]  

 

 

 

Chemical Name:  2-(4-heptylphenethyl)-6-hydroxybenzoic acid

 

MG 149 | Tip60 HAT inhibitor | Axon Medchem | Axon 1785 | MG149

axonmedchem.com © 2012

 

Axon Ligands in The Field:

 

Anacardic acid A | HAT inhibitor

MG 149 | Tip60 HAT inhibitor

 

ISOX | HDAC6 inhibitor

LBH 589 | HDAC inhibitor

SB 939 | HDAC inhibitor

 

 

Click Here To See Featured Cell Signaling and Oncology Ligands from Axon Ligands Collection