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PNU 100480

PF 02341272 - U 100480

 

 

CAS 168828-58-8

C16H20FN3O3S  MW 353.41

Purity: 99% (optically pure)

Soluble in DMSO to 100 mM

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1762   Prime Source

 

Qty1: 5 mg (research sample) / €135  $176 

Promotion: 2 x 5 mg @ €200  $260 

Qty2: 25 mg (research sample) / €435 $566

Promotion: 2 x 25 mg @ €660  $858

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

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Biological Activity:

 

Antituberculosis (anti-TB) agent under clinical development

 

References:

 

KN Williams et al. Promising Antituberculosis Activity of the Oxazolidinone PNU-100480 Relative to That of Linezolid in a Murine Model. Antimicrob Agents Chemother. 2009 April; 53(4): 1314–1319. [online] 

 
KN Williams et al. Addition of PNU-100480 to first-line drugs shortens the time needed to cure murine tuberculosis. Am. J. Respir. Crit. Care Med. 2009, 180(4), 371-6. [online]

 

Chemical Name: (S)-N-((3-(3-fluoro-4-thiomorpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide 
 

PNU 100480 | Anti-TB agent | Axon Medchem | PNU100480

 

Axon LigandsTM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Field:

 

PNU 100480 | Anti-TB agent