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(S)-(-)-Bay K 8644

(-)-Bay-K8644

CAS 98625-26-4

C16H15F3N2O4  MW 356.30

Purity: 99% (optically pure)

Soluble in DMSO and EtOH

Ordering Information:

Cat. No. Axon 1759     Prime Source

Qty1: 5 mg / €125  $163 

Qty2: 25 mg / €435  $566

Qty3: on request

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Biological Activity:   L-type Ca2+-channel activator with positive inotropic, vasoconstrictive and behavioral effects in vivo. (S)-Enantiomer of Bay K8644 (Axon 1697).   References:   FT Van Amsterdam et al. Stereoisomers of Bay K 8644 show opposite activities in the normal and ischemic rat heart. A comparison with nifedipine. Naunyn Schmiedebergs Arch. Pharmacol. 1989, 339, 647-652. [online]   J Ferrante et al. Binding of a 14-dihydropyridine calcium channel activator (−)-S-Bay K 8644 to cardiac preparations. Biochem. Biophys. Res. Commun. 1989, 158, 149-154. [online] M Sekiguchi-Tonosaki et al. Acetylcholine Induces Ca2+ Signaling In Chicken Retinal Pigmented Epithelial Cells During Dedifferentiation. Am. J. Physiol. Cell Physiol. 2009, 296, C1195-206. [online]     Chemical Name: (S)-(-)-Methyl 2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate

(S)-(-)-Bay K 8644 | Ca channel activator | Axon Medchem | Axon 1759 | (-)-BAY-K8644

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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