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BVT 2733 hydrochloride

CAS 376641-65-5 (HCl)

376640-41-4 (parent)

C17H21ClN4O4S2.HCl  MW 465.42

Purity: 99%

Soluble in DMSO

Ordering Information:

Cat. No. Axon 1756    Prime Source

Qty1: 5 mg / €115  $150

Qty2: 25 mg / €345  $449

Qty3: on request

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Biological Activity:   Selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11beta-HSD1 or HSD11B1).   References: P Alberts et al. Selective inhibition of 11 beta-hydroxysteroid dehydrogenase type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains. Endocrinology. 2003, 144(11), 4755-4762. [online] SJ Wang et al. Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 reduces food intake and weight gain but maintains energy expenditure in diet-induced obese mice. Diabetologia. 2006, 49(6), 1333-7. [online]     Chemical Name: 3-chloro-2-methyl-N-(4-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)thiazol-2-yl)benzenesulfonamide hydrochloride

BVT 2733 | 11beta-HSD1 inhibitor | Axon Medchem | Axon 1756 | BVT2733

Axon Ligands ^TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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