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Biological Activity:
Direct factor Xa inhibitor; being investigated as an anticoagulant.
References: online
CB Grange et al. Apixaban versus Warfarin in Patients with Atrial Fibrillation. N. Engl. J. Med. 2011, 365, 981-992. [online]
JH Alexander et al. Apixaban with antiplatelet therapy after acute coronary syndrome. N. Engl. J. Med. 2011, 365(8), 699-708. [online]
SJ Connolly et al. Apixaban in patients with atrial fibrillation. N. Engl. J. Med. 2011, 364(9), 806–817. [online]
Chemical Name: 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[5,4-c]pyridine-3-carboxamide
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